hyper-sensitive hits (gene name) ENSG name rho -log_pMannWhitney AASDHPPT ENSG00000149313 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -0.412460425 1.817111705 ACOT2 ENSG00000119673 Acyl-coenzyme A thioesterase 2, mitochondrial -0.490951822 1.861495617 AGPAT1 ENSG00000235758 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha -0.337606545 3.059104444 AGPS ENSG00000018510 Alkyldihydroxyacetonephosphate synthase, peroxisomal -0.540712388 1.117214491 AHR ENSG00000106546 Aryl hydrocarbon receptor -0.272401382 3.774502489 ANAPC2 ENSG00000176248 anaphase promoting complex subunit 2 -0.191958859 2.801810633 ARHGEF15 ENSG00000198844 Rho guanine nucleotide exchange factor 15 -0.241962574 2.248161589 ARRDC3 ENSG00000113369 Arrestin domain-containing protein 3 -0.250112719 2.025379117 ASNA1 ENSG00000198356 ATPase GET3 -0.239598153 2.283047784 ASPRV1 ENSG00000244617 Retroviral-like aspartic protease 1 -0.342184816 1.692020956 BRE ENSG00000158019 BRISC and BRCA1-A complex member 2 -0.299034499 2.444408023 BUD13 ENSG00000137656 BUD13 homolog -0.202727998 2.600430927 C21orf91 ENSG00000154642 Protein EURL homolog -0.307012848 2.851588948 C5 ENSG00000106804 Complement C5 -0.32800623 2.203027509 C6orf163 ENSG00000203872 Uncharacterized protein C6orf163 -0.224483095 2.235425518 C8B ENSG00000021852 Complement component C8 beta chain -0.369934463 2.06701204 CAMSAP2 ENSG00000118200 Calmodulin-regulated spectrin-associated protein 2 -0.285844765 2.060013422 CARM1 ENSG00000142453 Histone-arginine methyltransferase CARM1 -0.232006072 2.517989673 CCAR1 ENSG00000060339 Cell division cycle and apoptosis regulator protein 1 -0.507667441 1.953728323 CCDC92 ENSG00000119242 Coiled-coil domain-containing protein 92 -0.446398525 1.528595715 CENPF ENSG00000117724 Centromere protein F -0.202675711 2.517635574 CIT ENSG00000122966 Citron Rho-interacting kinase -0.312804686 4.104928558 CLTA ENSG00000122705 Clathrin light chain A -0.496093977 3.573703136 CLTC ENSG00000141367 Clathrin heavy chain 1 -0.462888318 2.192758992 CNIH1 ENSG00000100528 Protein cornichon homolog 1 -0.316907394 2.170282006 COASY ENSG00000068120 Bifunctional coenzyme A synthase -0.235807991 2.35457616 COIL ENSG00000121058 Coilin -0.210871906 2.433106371 CORO2B ENSG00000103647 Coronin-2B -0.407526228 2.073339177 COX17 ENSG00000138495 Cytochrome c oxidase copper chaperone -0.232446208 2.493667569 COX20 ENSG00000203667 Cytochrome c oxidase assembly protein COX20, mitochondrial -0.265814582 2.293404358 CTAGE5 ENSG00000150527 Melanoma inhibitory activity protein 2 -0.35214458 2.667623876 CTTNBP2NL ENSG00000143079 CTTNBP2 N-terminal-like protein -0.278691783 2.996717259 CUL4B ENSG00000158290 Cullin-4B -0.193026606 2.623839321 CYLC1 ENSG00000183035 Cylicin-1 -0.219685674 3.187635782 CYP51A1 ENSG00000001630 Lanosterol 14-alpha demethylase -0.857262882 2.137758185 DERL1 ENSG00000136986 Derlin-1 -0.297383213 3.017433425 DHCR24 ENSG00000116133 Delta -0.728503931 2.443053483 DNAJC13 ENSG00000138246 DnaJ homolog subfamily C member 13 -0.263632949 3.458695146 DNAJC24 ENSG00000170946 DnaJ homolog subfamily C member 24 -0.329780095 1.744978068 DPH1 ENSG00000108963 2- -0.264306215 2.198934216 DRAM1 ENSG00000136048 DNA damage-regulated autophagy modulator protein 1 -0.27379177 2.009183006 ELAVL1 ENSG00000066044 ELAV-like protein 1 -0.318164652 1.697433131 ELMSAN1 ENSG00000156030 Mitotic deacetylase-associated SANT domain protein -0.188597936 2.739880437 ELOVL5 ENSG00000012660 ELOVL fatty acid elongase 5 -0.487266694 2.861561131 EMG1 ENSG00000126749 Ribosomal RNA small subunit methyltransferase NEP1 -0.293982634 3.443791143 ERH ENSG00000100632 Enhancer of rudimentary homolog -0.333439096 1.92190878 EXOC4 ENSG00000131558 Exocyst complex component 4 -0.251870773 2.00462972 FAR2 ENSG00000064763 Fatty acyl-CoA reductase 2 -0.381753806 3.930163831 FASN ENSG00000169710 fatty acid synthase -0.697085477 3.297700661 FBXO8 ENSG00000164117 F-box only protein 8 -0.290936294 2.538928319 FOSL1 ENSG00000175592 Fos-related antigen 1 -0.243345128 2.136120565 FZD2 ENSG00000180340 Frizzled-2 -0.287904817 2.309062227 FZD6 ENSG00000164930 Frizzled-6 -0.37622286 1.855666961 GLOD5 ENSG00000171433 Glyoxalase domain-containing protein 5 -0.266109594 3.732938394 GOLPH3L ENSG00000143457 Golgi phosphoprotein 3-like -0.226512771 2.285665604 GOLT1B ENSG00000111711 Vesicle transport protein GOT1B -0.340918215 2.376606228 GOSR1 ENSG00000108587 Golgi SNAP receptor complex member 1 -0.23504955 2.349717138 GPI ENSG00000105220 Glucose-6-phosphate isomerase -0.288932827 2.385012124 GTSF1 ENSG00000170627 Gametocyte-specific factor 1 -0.298300466 2.557189551 HAMP ENSG00000105697 Hepcidin -0.195870083 2.665148732 HLA-DMB ENSG00000241674 HLA class II histocompatibility antigen, DM beta chain -0.568326358 1.101943448 HMGCR ENSG00000113161 3-hydroxy-3-methylglutaryl-coenzyme A reductase -0.368973478 4.002794109 HMGCS1 ENSG00000112972 Hydroxymethylglutaryl-CoA synthase, cytoplasmic -0.703468877 2.902783922 HNRNPM ENSG00000099783 Heterogeneous nuclear ribonucleoprotein M -0.240597813 2.191024806 HSP90AB1 ENSG00000096384 Heat shock protein HSP 90-beta -0.3307747 1.81498543 IMPDH2 ENSG00000178035 Inosine-5'-monophosphate dehydrogenase 2 -0.239162394 3.400478504 INA ENSG00000148798 Alpha-internexin -0.290347295 2.687882481 INPPL1 ENSG00000165458 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 -0.23306268 2.483052609 INTS5 ENSG00000185085 Integrator complex subunit 5 -0.279253573 3.900534026 IRX3 ENSG00000177508 Iroquois-class homeodomain protein IRX-3 -0.204069876 2.450308709 ITSN2 ENSG00000198399 Intersectin-2 -0.224378358 2.308230066 JTB ENSG00000143543 Protein JTB -0.363786265 3.495922568 KCNK5 ENSG00000164626 Potassium channel subfamily K member 5 -0.300112489 2.296460899 KCTD7 ENSG00000243335 BTB/POZ domain-containing protein KCTD7 -0.382420343 1.986793501 KDM1A ENSG00000004487 Lysine-specific histone demethylase 1A -0.236785198 2.895730424 KHSRP ENSG00000088247 Far upstream element-binding protein 2 -0.361131341 4.196254833 KIAA0226 ENSG00000145016 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein -0.3639608 2.698735319 KIAA0922 ENSG00000121210 Transmembrane protein 131-like -0.219208445 2.632687248 KIAA1109 ENSG00000138688 Transmembrane protein KIAA1109 -0.351342704 1.970113051 KIAA1432 ENSG00000107036 Guanine nucleotide exchange factor subunit RIC1 -0.264652678 2.394128493 KIF4A ENSG00000090889 Chromosome-associated kinesin KIF4A -0.332708607 1.586936984 LAPTM5 ENSG00000162511 Lysosomal-associated transmembrane protein 5 -0.523938747 4.696211803 LIMD2 ENSG00000136490 LIM domain-containing protein 2 -0.282331734 2.193031002 LIPN ENSG00000204020 Lipase member N -0.378315567 2.515194583 LRBA ENSG00000198589 Lipopolysaccharide-responsive and beige-like anchor protein -0.322213396 1.962128049 MAT2B ENSG00000038274 Methionine adenosyltransferase 2 subunit beta -0.356849667 3.5600262 MMD ENSG00000108960 Monocyte to macrophage differentiation factor -0.41052947 4.025097793 MSMO1 ENSG00000052802 Methylsterol monooxygenase 1 -0.44420418 2.27558766 NAPG ENSG00000134265 Gamma-soluble NSF attachment protein -0.305869405 2.287899653 NDUFB11 ENSG00000147123 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial -0.343962368 3.082337724 NETO2 ENSG00000171208 Neuropilin and tolloid-like protein 2 -0.243606304 2.525087561 NFE2 ENSG00000123405 Transcription factor NF-E2 45 kDa subunit -0.282669748 4.240438395 NR2E3 ENSG00000278570 Photoreceptor-specific nuclear receptor -0.326447043 2.754936615 NSDHL ENSG00000147383 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating -0.3464817 2.754174335 PDE12 ENSG00000174840 2',5'-phosphodiesterase 12 -0.2052012 2.544566402 PDLIM2 ENSG00000120913 PDZ and LIM domain protein 2 -0.260858386 2.173120511 PDXDC1 ENSG00000275498 Pyridoxal-dependent decarboxylase domain-containing protein 1 -0.264448641 1.915211021 PEX7 ENSG00000112357 Peroxisomal targeting signal 2 receptor -0.277129303 2.187802933 PGK1 ENSG00000102144 Phosphoglycerate kinase 1 -0.322618458 3.415144016 PHC2 ENSG00000134686 Polyhomeotic-like protein 2 -0.22447512 2.677822875 PHF6 ENSG00000156531 PHD finger protein 6 -0.408145129 2.305456739 PI4K2B ENSG00000038210 Phosphatidylinositol 4-kinase type 2-beta -0.651788122 4.836345239 PI4KB ENSG00000143393 Phosphatidylinositol 4-kinase beta -0.350488511 3.113963899 PKM ENSG00000067225 Pyruvate kinase PKM -0.26647013 3.213730478 PLEKHB2 ENSG00000115762 Pleckstrin homology domain-containing family B member 2 -0.291140433 2.58983054 POLR1E ENSG00000137054 DNA-directed RNA polymerase I subunit RPA49 -0.318738136 2.344916293 PPP2CA ENSG00000113575 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform -0.315332401 2.508583416 PREB ENSG00000138073 Prolactin regulatory element-binding protein -0.416939781 1.631084388 PRMT6 ENSG00000198890 Protein arginine N-methyltransferase 6 -0.198591968 3.117050627 PRR5 ENSG00000186654 Proline-rich protein 5 -0.339823996 2.135790249 PUM1 ENSG00000134644 Pumilio homolog 1 -0.384686921 2.488357206 PYROXD2 ENSG00000119943 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 -0.304823946 1.679046643 RAB10 ENSG00000084733 Ras-related protein Rab-10 -0.252306522 2.305889273 RAB14 ENSG00000119396 Ras-related protein Rab-14 -0.506759757 2.249154557 RAB1A ENSG00000138069 Ras-related protein Rab-1A -0.355275666 2.217944834 RAB9B ENSG00000123570 Ras-related protein Rab-9B -0.235495458 2.227132527 RABGEF1 ENSG00000154710 Rab5 GDP/GTP exchange factor -0.437243142 2.438473043 RBM15 ENSG00000162775 RNA-binding protein 15 -0.233029109 2.724950672 RBM33 ENSG00000184863 RNA-binding protein 33 -0.272440691 1.893878466 RNF146 ENSG00000118518 E3 ubiquitin-protein ligase RNF146 -0.275744527 1.85234041 RNF224 ENSG00000233198 RING finger protein 224 -0.270828902 2.347310467 RPS29 ENSG00000213741 40S ribosomal protein S29 -0.231060337 2.492373747 SAR1A ENSG00000079332 GTP-binding protein SAR1a -0.380703461 1.913802462 SBK3 ENSG00000231274 Uncharacterized serine/threonine-protein kinase SBK3 -0.350245611 2.277355435 SC5D ENSG00000109929 Lathosterol oxidase -0.258686777 4.088344888 SCOC ENSG00000153130 Short coiled-coil protein -0.36683487 1.900096267 SCYL2 ENSG00000136021 SCY1-like protein 2 -0.489206822 4.53887917 SEC22B ENSG00000265808 Vesicle-trafficking protein SEC22b -0.461784518 3.473400556 SEC23B ENSG00000101310 Protein transport protein Sec23B -0.485274124 3.231906184 SEC23IP ENSG00000107651 SEC23-interacting protein -0.228232543 2.97544389 SEC24A ENSG00000113615 Protein transport protein Sec24A -0.258026312 3.357704874 SEC24B ENSG00000138802 Protein transport protein Sec24B -0.348176282 1.836097302 SEC24C ENSG00000176986 Protein transport protein Sec24C -0.367846577 2.660819892 SECISBP2L ENSG00000138593 Selenocysteine insertion sequence-binding protein 2-like -0.249217247 2.07758839 SEMA3A ENSG00000075213 Semaphorin-3A -0.273759009 1.837815577 SETX ENSG00000107290 Probable helicase senataxin -0.241859186 2.330557047 SHOC2 ENSG00000108061 Leucine-rich repeat protein SHOC-2 -0.37536026 4.122243058 SLC35E1 ENSG00000127526 Solute carrier family 35 member E1 -0.374778848 1.54377242 SLC39A9 ENSG00000029364 Zinc transporter ZIP9 -0.371407965 2.131211508 SLC40A1 ENSG00000138449 Solute carrier family 40 member 1 -0.296008611 1.766897994 SNAI1 ENSG00000124216 Zinc finger protein SNAI1 -0.26396303 3.011858777 SNX14 ENSG00000135317 Sorting nexin-14 -0.291466526 3.241566188 SP1 ENSG00000185591 Transcription factor Sp1 -0.39787168 1.78636849 SPHK2 ENSG00000063176 Sphingosine kinase 2 -0.312707127 1.882908436 SPTY2D1 ENSG00000179119 Protein SPT2 homolog -0.258393225 2.04515698 SREBF2 ENSG00000198911 Sterol regulatory element-binding protein 2 -0.627758897 5.455760379 SRSF9 ENSG00000111786 Serine/arginine-rich splicing factor 9 -0.215140998 2.538713579 SURF4 ENSG00000148248 Surfeit locus protein 4 -0.442720928 3.015849891 TKT ENSG00000163931 Transketolase -0.375196613 3.15951924 TMED10 ENSG00000170348 Transmembrane emp24 domain-containing protein 10 -0.401021159 5.902636221 TMED2 ENSG00000086598 Transmembrane emp24 domain-containing protein 2 -0.321164832 2.310515239 TMEM131 ENSG00000075568 Transmembrane protein 131 -0.201425778 2.791311847 TMEM191C ENSG00000206140 Transmembrane protein 191C -0.268303324 2.290571641 TMEM205 ENSG00000105518 Transmembrane protein 205 -0.410438885 1.693573594 TRAPPC12 ENSG00000171853 Trafficking protein particle complex subunit 12 -0.471487693 1.845627129 TRAPPC13 ENSG00000113597 Trafficking protein particle complex subunit 13 -0.394362563 4.569926361 TRAPPC8 ENSG00000153339 Trafficking protein particle complex subunit 8 -0.298519659 4.388187388 TRIM32 ENSG00000119401 E3 ubiquitin-protein ligase TRIM32 -0.309843288 2.359113239 TRIP11 ENSG00000100815 Thyroid receptor-interacting protein 11 -0.311024554 2.140960821 TSPAN3 ENSG00000140391 Tetraspanin-3 -0.239656883 2.097966494 TSSC1 ENSG00000032389 EARP and GARP complex-interacting protein 1 -0.293303561 3.459361523 UBR4 ENSG00000127481 E3 ubiquitin-protein ligase UBR4 -0.21129354 3.366429615 UGT3A2 ENSG00000168671 UDP-glucuronosyltransferase 3A2 -0.672524161 1.194167318 USE1 ENSG00000053501 Vesicle transport protein USE1 -0.41370394 5.037206243 VAMP4 ENSG00000117533 Vesicle-associated membrane protein 4 -0.253255007 2.235653986 VPS4A ENSG00000132612 Vacuolar protein sorting-associated protein 4A -0.282652867 2.34032705 VPS54 ENSG00000143952 Vacuolar protein sorting-associated protein 54 -0.469142083 1.183135263 VPS72 ENSG00000163159 Vacuolar protein sorting-associated protein 72 homolog -0.398660483 3.07808323 WDR45 ENSG00000196998 WD repeat domain phosphoinositide-interacting protein 4 -0.251718781 2.743195977 WWOX ENSG00000186153 WW domain-containing oxidoreductase -0.255081025 2.315802414 XPR1 ENSG00000143324 Xenotropic and polytropic retrovirus receptor 1 -0.224204037 2.462950522 ZC3H15 ENSG00000065548 Zinc finger CCCH domain-containing protein 15 -0.25176958 2.404886254 ZCCHC4 ENSG00000168228 rRNA N6-adenosine-methyltransferase ZCCHC4 -0.283821012 2.549041938 ZDHHC12 ENSG00000160446 Probable palmitoyltransferase ZDHHC12 -0.241750154 2.160302384 ZFP91 ENSG00000186660 E3 ubiquitin-protein ligase ZFP91 -0.28577702 1.935481152 ZFYVE20 ENSG00000131381 Rabenosyn-5 -0.237688646 2.355514502 ZRANB2 ENSG00000132485 Zinc finger Ran-binding domain-containing protein 2 -0.398219461 2.439193562 ZSCAN20 ENSG00000121903 Zinc finger and SCAN domain-containing protein 20 -0.227779481 3.127144378