MP vs. NMP MP-MF vs. NMP-MF MP vs. MP-MF NMP vs. NMP-MF Annotation results from BLAST2GO Locus Tag log2FC (MP relative to NMP) p-adj log2FC (MP relative to NMP) p-adj log2FC (Control relative to MF) p-adj log2FC (Control relative to MF) p-adj Description GO IDs GO Names Enzyme Codes Enzyme Names APZ42_017529 -2.0839 3.18E-08 NA P:GO:0043085; F:GO:0008047; P:GO:0006689 P:positive regulation of catalytic activity; F:enzyme activator activity; P:ganglioside catabolic process APZ42_000119 -2.9213 1.88E-28 NA F:GO:0015035; C:GO:0016021; P:GO:0055114 F:protein disulfide oxidoreductase activity; C:integral component of membrane; P:oxidation-reduction process APZ42_000790 2.9860 2.56E-11 transmembrane protease serine 11E C:GO:0016020; C:GO:0044464; F:GO:0008233 C:membrane; C:cell part; F:peptidase activity APZ42_001100 -6.0292 1.90E-89 -6.7252 2.07E-72 tectonin beta-propeller repeat-containing 2-like APZ42_001141 -3.3385 2.52E-14 -2.9702 3.55E-08 NA APZ42_001879 -2.7013 1.21E-08 -3.3751 2.77E-11 THO complex subunit 4 F:GO:0000166; F:GO:0003676; C:GO:0016020; C:GO:0016021 F:nucleotide binding; F:nucleic acid binding; C:membrane; C:integral component of membrane APZ42_002100 -2.2031 2.93E-07 NA APZ42_002154 2.1317 1.06E-03 Delta-1-pyrroline-5-carboxylate mitochondrial P:GO:0008152; F:GO:0016620 "P:metabolic process; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" APZ42_002526 -2.8532 2.06E-09 -2.9345 1.68E-07 NA APZ42_003182 -2.2077 6.57E-10 NA APZ42_003885 -3.2025 6.82E-33 NA APZ42_003886 -2.3516 5.45E-08 NA APZ42_003946 -2.4954 7.13E-13 NA APZ42_004029 -2.0604 3.09E-10 hypothetical protein DAPPUDRAFT_70492 APZ42_004030 -2.3067 8.88E-13 NA APZ42_004189 -2.8343 6.74E-14 -3.2077 1.27E-17 NA APZ42_004358 -2.5108 2.86E-17 proto-oncogene tyrosine- kinase receptor Ret-like F:GO:0005525; C:GO:0016020; C:GO:0016021 F:GTP binding; C:membrane; C:integral component of membrane APZ42_004611 -3.0441 4.88E-10 NA APZ42_005104 -2.2570 3.31E-18 NA APZ42_005111 -6.5871 1.33E-111 -5.6689 3.20E-47 NA F:GO:0003676; F:GO:0008270 F:nucleic acid binding; F:zinc ion binding APZ42_005136 -2.1544 3.30E-07 Lysosomal alpha-glucosidase P:GO:0005975; C:GO:0016021; F:GO:0004553; F:GO:0030246 "P:carbohydrate metabolic process; C:integral component of membrane; F:hydrolase activity, hydrolyzing O-glycosyl compounds; F:carbohydrate binding" APZ42_005240 -2.0206 7.92E-06 c-type lectin ctl - mannose APZ42_005244 -2.1224 1.58E-04 NA APZ42_005291 -2.0145 4.96E-04 -2.0550 3.42E-03 Alpha--fucosyltransferase C F:GO:0016757; F:GO:0008417; C:GO:0032580; P:GO:0036065; C:GO:0016020; C:GO:0016021; P:GO:0006486; C:GO:0005794; F:GO:0016740 "F:transferase activity, transferring glycosyl groups; F:fucosyltransferase activity; C:Golgi cisterna membrane; P:fucosylation; C:membrane; C:integral component of membrane; P:protein glycosylation; C:Golgi apparatus; F:transferase activity" APZ42_005540 -2.1799 1.15E-05 -2.8718 6.49E-11 NA APZ42_007115 -2.8231 4.80E-08 NA APZ42_007323 -5.1204 1.17E-70 -4.8179 2.06E-50 NA APZ42_007388 -3.0842 2.05E-75 cell wall-associated hydrolase F:GO:0016787 F:hydrolase activity APZ42_007558 -2.2407 3.27E-13 chitinase F:GO:0004568; P:GO:0005975; F:GO:0008061; P:GO:0006032; C:GO:0005576 F:chitinase activity; P:carbohydrate metabolic process; F:chitin binding; P:chitin catabolic process; C:extracellular region EC:3.2.1.14 Chitinase APZ42_007763 -6.1778 1.65E-91 -5.4922 4.88E-45 NA APZ42_008254 -2.2520 8.18E-06 NA APZ42_008486 -2.3545 2.09E-09 NA APZ42_009228 -2.4456 6.92E-07 -2.3296 1.04E-04 NA APZ42_012672 -2.0847 1.55E-17 NA C:GO:0016020; C:GO:0016021 C:membrane; C:integral component of membrane APZ42_012681 -2.5144 4.52E-13 NA F:GO:0015035; C:GO:0016021; P:GO:0055114 F:protein disulfide oxidoreductase activity; C:integral component of membrane; P:oxidation-reduction process APZ42_014553 -2.2627 1.18E-10 -2.2083 1.79E-07 prolyl 4-hydroxylase subunit alpha-2-like F:GO:0004656; F:GO:0031418; F:GO:0016702; F:GO:0005506; C:GO:0005783; P:GO:0019511; P:GO:0055114 "F:procollagen-proline 4-dioxygenase activity; F:L-ascorbic acid binding; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; F:iron ion binding; C:endoplasmic reticulum; P:peptidyl-proline hydroxylation; P:oxidation-reduction process" EC:1.13.11; EC:1.14.11; EC:1.14.11.2 "Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O(2); Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2); Procollagen-proline dioxygenase" APZ42_015686 -2.0032 1.10E-06 Peritrophic matrix F:GO:0008061; P:GO:0006030; C:GO:0005576 F:chitin binding; P:chitin metabolic process; C:extracellular region APZ42_016110 -2.0402 2.84E-15 Serine threonine- kinase endoribonuclease IRE2 F:GO:0005524; F:GO:0004674; P:GO:0006468 F:ATP binding; F:protein serine/threonine kinase activity; P:protein phosphorylation EC:2.7.11 Transferring phosphorus-containing groups APZ42_017193 -2.9075 5.40E-16 Sulfotransferase family cytosolic 1B member F:GO:0008146 F:sulfotransferase activity APZ42_017734 -2.0500 8.40E-27 flotillin-1 isoform X2 APZ42_017775 -2.5945 6.92E-08 -2.5564 2.04E-05 NA APZ42_017776 -3.0668 1.25E-11 -3.5177 1.03E-11 NA APZ42_018397 -2.1534 1.11E-09 sodium-dependent nutrient amino acid transporter 1-like C:GO:0005887; P:GO:0006836; F:GO:0005328; P:GO:0055085 C:integral component of plasma membrane; P:neurotransmitter transport; F:neurotransmitter:sodium symporter activity; P:transmembrane transport APZ42_019026 2.2039 1.06E-03 NA C:GO:0016021 C:integral component of membrane APZ42_019037 2.5684 1.34E-07 Chymotrypsin-like serine ase P:GO:0006508; C:GO:0016020; C:GO:0016021; F:GO:0004252; F:GO:0008236; F:GO:0008233; F:GO:0016787 P:proteolysis; C:membrane; C:integral component of membrane; F:serine-type endopeptidase activity; F:serine-type peptidase activity; F:peptidase activity; F:hydrolase activity APZ42_019037 2.5684 1.34E-07 serine protease SP24D F:GO:0008236 F:serine-type peptidase activity APZ42_019039 -2.2345 3.90E-19 elongation factor 2 kinase F:GO:0005524; F:GO:0004674; P:GO:0006468 F:ATP binding; F:protein serine/threonine kinase activity; P:protein phosphorylation EC:2.7.11 Transferring phosphorus-containing groups APZ42_021099 -2.4443 6.53E-11 Poly(3-hydroxyalkanoate) depolymerase C C:GO:0005576 C:extracellular region APZ42_021101 -2.0424 3.18E-06 Poly(3-hydroxyalkanoate) depolymerase C C:GO:0005576 C:extracellular region APZ42_021419 -3.0775 3.62E-17 NA C:GO:0016021 C:integral component of membrane APZ42_021606 -2.0890 1.50E-06 Hemoglobin C:GO:0005833; F:GO:0019825; F:GO:0005506; P:GO:0015671; C:GO:0005576; F:GO:0005344; F:GO:0020037 C:hemoglobin complex; F:oxygen binding; F:iron ion binding; P:oxygen transport; C:extracellular region; F:oxygen transporter activity; F:heme binding APZ42_021661 -3.3474 1.67E-28 NA F:GO:0008061; P:GO:0006030; C:GO:0005576 F:chitin binding; P:chitin metabolic process; C:extracellular region APZ42_024553 -2.0139 2.44E-06 4-aminobutyrate mitochondrial F:GO:0030170; F:GO:0042802; F:GO:0003867; C:GO:0005739; P:GO:0009450 F:pyridoxal phosphate binding; F:identical protein binding; F:4-aminobutyrate transaminase activity; C:mitochondrion; P:gamma-aminobutyric acid catabolic process EC:2.6.1.19 4-aminobutyrate--2-oxoglutarate transaminase APZ42_024615 -2.1953 2.90E-20 Regulator of rDNA transcription 15 APZ42_024616 -2.2967 4.48E-17 NA APZ42_025333 -3.5585 3.19E-15 -6.2669 5.22E-68 NA P:GO:0090502; F:GO:0003676; F:GO:0004523 "P:RNA phosphodiester bond hydrolysis, endonucleolytic; F:nucleic acid binding; F:RNA-DNA hybrid ribonuclease activity" APZ42_025441 -2.1402 2.78E-07 4-coumarate-- ligase 3 P:GO:0008152; F:GO:0016874 P:metabolic process; F:ligase activity APZ42_025443 -2.0868 2.19E-03 4-coumarate-- ligase 3 P:GO:0008152; F:GO:0016874 P:metabolic process; F:ligase activity APZ42_026030 -2.1988 8.51E-06 -3.0945 2.49E-20 NA APZ42_027571 2.3874 3.64E-06 NA APZ42_028139 -2.4179 1.15E-12 Sulfotransferase family cytosolic 1B member F:GO:0008146 F:sulfotransferase activity APZ42_028140 -2.2768 6.46E-08 -2.3218 1.50E-15 Dehydrogenase reductase SDR family member 4 F:GO:0004090; P:GO:0055114 F:carbonyl reductase (NADPH) activity; P:oxidation-reduction process EC:1.1.1.184 Carbonyl reductase (NADPH) APZ42_028520 -2.2308 1.15E-12 bifunctional 3 -phosphoadenosine 5 -phosphosulfate synthase 2 isoform X1 F:GO:0005524; P:GO:0050428; F:GO:0004020; F:GO:0004781; P:GO:0007596; P:GO:0016310; P:GO:0000103; P:GO:0060348 F:ATP binding; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; F:adenylylsulfate kinase activity; F:sulfate adenylyltransferase (ATP) activity; P:blood coagulation; P:phosphorylation; P:sulfate assimilation; P:bone development EC:2.7.7.4; EC:2.7.1.25 Sulfate adenylyltransferase; Adenylyl-sulfate kinase APZ42_029168 2.4427 3.58E-09 Serine protease 33 P:GO:0006508; F:GO:0004252 P:proteolysis; F:serine-type endopeptidase activity EC:3.4.21 Acting on peptide bonds (peptidases) APZ42_030072 -2.6352 7.20E-10 4-coumarate-- ligase 3 F:GO:0003824; P:GO:0008152 F:catalytic activity; P:metabolic process APZ42_030230 2.9986 1.69E-10 4.5963 2.73E-45 NA F:GO:0004601; P:GO:0006979; P:GO:0098869; P:GO:0055114; C:GO:0042600; F:GO:0020037 F:peroxidase activity; P:response to oxidative stress; P:cellular oxidant detoxification; P:oxidation-reduction process; C:chorion; F:heme binding EC:1.11.1.7 Peroxidase APZ42_030387 2.0573 1.80E-16 NA C:GO:0005615; F:GO:0004197; P:GO:0051603; C:GO:0005764 C:extracellular space; F:cysteine-type endopeptidase activity; P:proteolysis involved in cellular protein catabolic process; C:lysosome EC:3.4.22 Acting on peptide bonds (peptidases) APZ42_030438 -2.0372 1.10E-10 Maltase A6 P:GO:0005975; C:GO:0016021; F:GO:0016798 "P:carbohydrate metabolic process; C:integral component of membrane; F:hydrolase activity, acting on glycosyl bonds" APZ42_030656 -2.6707 2.84E-14 C-type lectin domain family 4 member E F:GO:0030246 F:carbohydrate binding APZ42_031465 -3.9536 1.56E-22 -3.8070 6.54E-17 NA P:GO:0090502; F:GO:0003676; F:GO:0004523 "P:RNA phosphodiester bond hydrolysis, endonucleolytic; F:nucleic acid binding; F:RNA-DNA hybrid ribonuclease activity" APZ42_031630 -2.3249 4.07E-22 NA C:GO:0016020; C:GO:0016021 C:membrane; C:integral component of membrane APZ42_032826 -2.5826 1.75E-11 Pancreatic lipase-related 2 C:GO:0005576; F:GO:0052689 C:extracellular region; F:carboxylic ester hydrolase activity EC:3.1.1.1 Carboxylesterase APZ42_033829 -2.1101 2.87E-07 C-type lectin domain family 4 member E F:GO:0030246 F:carbohydrate binding APZ42_034017 -2.3950 4.95E-20 chitinase F:GO:0004568; P:GO:0005975; F:GO:0008061; P:GO:0006032; C:GO:0005576 F:chitinase activity; P:carbohydrate metabolic process; F:chitin binding; P:chitin catabolic process; C:extracellular region EC:3.2.1.14 Chitinase APZ42_034281 -3.7063 4.15E-21 -3.9704 3.80E-24 NA APZ42_034532 -2.0063 1.73E-04 -2.6128 1.32E-05 NA F:GO:0003676 F:nucleic acid binding APZ42_034582 -2.2981 1.01E-19 "beta-1,4-N-acetylgalactosaminyltransferase bre-4-like isoform X1" P:GO:0005975; F:GO:0016757 "P:carbohydrate metabolic process; F:transferase activity, transferring glycosyl groups" APZ42_030578 1.1302 4.09E-02 -1.1466 4.37E-03 NA APZ42_030743 1.1825 2.62E-02 -1.1626 4.13E-03 Down syndrome cell adhesion molecule Dscam2 C:GO:0016021 C:integral component of membrane APZ42_019037 1.5150 1.26E-03 -1.5949 3.26E-04 Chymotrypsin-like serine ase P:GO:0006508; C:GO:0016020; C:GO:0016021; F:GO:0004252; F:GO:0008236; F:GO:0008233; F:GO:0016787 P:proteolysis; C:membrane; C:integral component of membrane; F:serine-type endopeptidase activity; F:serine-type peptidase activity; F:peptidase activity; F:hydrolase activity APZ42_000790 1.4499 3.64E-03 -1.6886 4.76E-05 transmembrane protease serine 11E C:GO:0016020; C:GO:0044464; F:GO:0008233 C:membrane; C:cell part; F:peptidase activity "NOTE: The last four genes of the list are not strongly DE (p-adj < 0,05, |log2FC| > 2) in the given contrast, but they showed a differential reaction to hormone exposure between the two phenotypes."