<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:contributor>Rothen-Rutishauser, Barbara</dc:contributor>
  <dc:creator>Ivasiv, Viktoriya</dc:creator>
  <dc:date>2026</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Chemodynamic therapy (CDT) has emerged as a promising cancer treatment strategy leveraging tumor microenvironmentconditions to generate reactive oxygen species (ROS) through Fenton-type reactions. This study reports the synthesis, in-depthcharacterization, and biological evaluation of novel manganese-based zeolitic imidazolate framework (ZIF) nanoparticles, ie, Mn-rods, as a carrier-free potential CDT platform with exceptionally high manganese loading.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/335025</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/335025/files/Ivasiv_Exploring_2026.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>https://www.dovepress.com/exploring-the-potential-role-of-manganese-based-zeolitic-imidazolate-f-peer-reviewed-fulltext-article-IJN</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.2147/IJN.S578869</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/issn/1178-2013</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>CC BY</dc:rights>
  <dc:source>International Journal of Nanomedicine. - 2026, vol. 21, p. 1-21</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Chemodynamic therapy</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en"> Reactive oxygen species</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Tumor microenvironment</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en"> Lipid peroxidation</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Ferroptosis</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Nanomedicine</dc:subject>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns7="xml" ns7:lang="en">Exploring the Potential Role of Manganese-Based Zeolitic Imidazolate Framework Nanoparticles in Cancer Therapy: In vitro Studies Using Lung Cancer Cells</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>