<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Centner, Christoph</dc:creator>
  <dc:creator>Lauber, Benedikt</dc:creator>
  <dc:date>2020-08-04</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Objective: To summarize the existing evidence on the long-term effects of low-load  (LL) blood flow restricted (BFR) exercise on neural markers including both central and  peripheral adaptations.Methods: A systematic review and meta-analysis was  conducted according to the PRISMA guidelines. The literature search was performed  independently by two reviewers in the following electronic databases: PubMed, Web  of Science, Scopus and CENTRAL. The systematic review included long-term trials  investigating the effects of LL-BFR training in healthy subjects and compared theses  effects to either LL or high-load (HL) training without blood flow restriction.Results:  From a total of N = 4499 studies, N = 10 studies were included in the qualitative  synthesis and N = 4 studies in a meta-analysis. The findings indicated that LL-BFR  resulted in enhanced levels of muscle excitation compared to LL training with pooled  effect sizes of 0.87 (95% CI: 0.38–1.36). Compared to HL training, muscle excitation  following LL-BFR was reported as either similar or slightly lower. Differences between  central activation between LL-BFR and LL or HL are less clear.Conclusion: The  summarized effects in this systematic review and meta-analysis highlight that BFR  training facilitates neural adaptations following LL training, although differences to  conventional HL training are less evident. Future research is urgently needed to  identify neural alterations following long-term blood flow restricted exercise.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/308957</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/308957/files/lau_srm.pdf</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/308957/files/lau_srm_sm.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.3389/fphys.2020.00887</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Frontiers in Physiology. - 2020, vol. 11, p. 887</dc:source>
  <dc:subject>info:eu-repo/classification/udc/796</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">A systematic review and meta-analysis on neural adaptations following blood flow restriction training: what we know and what we don’t know</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>