Chabert, Valentin Babel, Lucille Füeg, Michael P. Karamash, Maksym Madivoli, Edwin S. Herault, Nelly Dantas, Joana M. Salgueiro, Carlos A. Giese, Bernd Fromm, Katharina M. 2019-12-09 Anaerobic microorganisms of the Geobacter genus are effective electron sources for the synthesis of nanoparticles, for bioremediation of polluted water, and for the production of electricity in fuel cells. In multistep reactions, electrons are transferred via iron/heme cofactors of c‐type cytochromes from the inner cell membrane to extracellular metal ions, which are bound to outer membrane cytochromes. We measured electron production and electron flux rates to 5×105 e s−1 per G.  sulfurreducens. Remarkably, these rates are independent of the oxidants, and follow zero order kinetics. It turned out that the microorganisms regulate electron flux rates by increasing their Fe2+/Fe3+ ratios in the multiheme cytochromes whenever the activity of the extracellular metal oxidants is diminished. By this mechanism the respiration remains constant even when oxidizing conditions are changing. This homeostasis is a vital condition for living systems, and makes G. sulfurreducens a versatile electron source. application/pdf https://folia.unifr.ch/global/documents/308585 https://folia.unifr.ch/documents/308585/files/fro_kmm.pdf https://folia.unifr.ch/documents/308585/files/fro_kmm_sm.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.1002/anie.201914873 info:eu-repo/semantics/openAccess License undefined Angewandte Chemie International Edition. - 2020, vol. 59, no. 30, p. 12331-12336 info:eu-repo/classification/udc/54 Kinetics and mechanism of mineral respiration: how iron hemes synchronize electron transfer rates http://purl.org/coar/resource_type/c_6501