<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Ramette, A.</dc:creator>
  <dc:creator>Kronenberg, A.</dc:creator>
  <dc:creator>Swiss Centre for Antibiotic Resistance (ANRESIS)</dc:creator>
  <dc:date>2018-04-03</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Background : We describe the prevalence of invasive carbapenem-resistant  Acinetobacter spp. isolated from 2005 to 2016 in different regions of  Switzerland.Methods: Using the Swiss Antibiotic Resistance Centre (anresis)  database that includes data from 70% of all hospitalized patients and one third of all  ambulatory practitioners in Switzerland, we analysed the number of carbapenem- susceptible and resistant Acinetobacter spp. isolated from blood or cerebrospinal fluid,  and further described their temporal and regional fluctuations.Results: From 2005 to  2016, 58 cases of resistant or intermediate strains to carbapenem were observed  among 632 cases of invasive Acinetobacter. Multivariable analyses indicated that the  number of carbapenem-resistant isolates (mean 4.8 ± sd 2.12) and carbapenem  resistance rates per region per annum (8.4% ± 13.9%) were low and stable over the  studied period. Large fluctuations were observed at the regional level, with e.g. the  North East region displaying resistance rates twice as high as that found in other  regions.Conclusion: Despite a relatively stable number of carbapenem-resistant  Acinetobacter isolates in Switzerland, our results suggest the existence of a diverse  pool of A. baumannii species in hospital settings, and confirm the implication of  carbapenem-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB)  complex in the vast majority of clinical infections and nosocomial outbreaks with  notable regional fluctuations.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/307758</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/307758/files/nor_pcr.pdf</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/307758/files/nor_pcr_sm.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1186/s12879-018-3061-5</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>BMC Infectious Diseases. - 2018, vol. 18, no. 1, p. 159</dc:source>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">Prevalence of carbapenem-resistant Acinetobacter baumannii from 2005 to 2016 in Switzerland</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>