<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Kieffer, Nicolas</dc:creator>
  <dc:creator>Nordmann, Patrice</dc:creator>
  <dc:creator>Moreno, Andrea Micke</dc:creator>
  <dc:creator>Zanolli Moreno, Luisa</dc:creator>
  <dc:creator>Chaby, Richard</dc:creator>
  <dc:creator>Breton, Aude</dc:creator>
  <dc:creator>Tissières, Pierre</dc:creator>
  <dc:creator>Poirel, Laurent</dc:creator>
  <dc:date>2018-07-01</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">A collection of 126 pigs was screened for carriage of colistin-resistant  Enterobacteriaceae in a farm in Minas Gerais, Brazil. Out of this collection, eight  colistin-resistant Escherichia coli isolates were recovered, including one from Minas  Gerais State producing a new MCR-3 variant (MCR-3.12). Analysis of the  lipopolysaccharide revealed that MCR-3.12 had a function similar to that of MCR-1  and MCR-2 as a result of the addition of a phosphoethanolamine group to the lipid A  moiety. Genetic analysis showed that the mcr-3.12 gene was carried by an IncA/C2  plasmid and was embedded in an original genetic environment. This study reports the  occurrence of the MCR-3-like determinant in South America and is the first to  demonstrate the functionality of this group of enzymes as a phosphoethanolamine  transferase.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/307107</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/307107/files/nor_gfc.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1128/AAC.00278-18</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Antimicrobial Agents and Chemotherapy. - 2018, vol. 62, no. 7, p. e00278-18</dc:source>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">Genetic and Functional Characterization of an MCR-3-Like Enzyme-Producing Escherichia coli Isolate Recovered from Swine in Brazil</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>