<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Sallard, Etienne</dc:creator>
  <dc:creator>Mouthon, Michaël</dc:creator>
  <dc:creator>De Pretto, Michael</dc:creator>
  <dc:creator>Spierer, Lucas</dc:creator>
  <dc:date>2018-03-28</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Prefrontal anodal transcranial direct current stimulation (tDCS) has been proposed as  a potential approach to improve inhibitory control performance. The functional  consequences of tDCS during inhibition tasks remain, however, largely unresolved.  We addressed this question by analyzing functional magnetic resonance imaging  (fMRI) recorded while participants completed a Go/NoGo task after right-lateralized  prefrontal anodal tDCS with a crossover, sham-controlled, double-blind experimental  design. We replicated previous evidence for an absence of offline effect of anodal  stimulation on Go/NoGo performance. The fMRI results revealed a larger increase in  right ventrolateral prefrontal activity for Go than NoGo trials in the anodal than sham  condition. This pattern suggests that tDCS-induced increases in cortical excitability  have larger effects on fMRI activity in regions with a lower task-related engagement.  This was the case for the right prefrontal cortex in the Go condition in our task  because while reactive inhibition was not engaged during execution trials, the  unpredictability of the demand for inhibitory control still incited an engagement of  proactive inhibition. Exploratory analyses further revealed that right prefrontal  stimulation interacted with task-related functional demands in the supplementary  motor area and the thalamus. Our collective results emphasize the dependency of  offline tDCS functional effects on the task-related engagement of the stimulated areas  and suggest that this factor might partly account for the discrepancies in the functional  effects of tDCS observed in previous studies.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/306618</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/306618/files/spi_mic.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0194936</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>PLOS ONE. - 2018, vol. 13, no. 3, p. e0194936</dc:source>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">Modulation of inhibitory control by prefrontal anodal tDCS: A crossover double-blind sham-controlled fMRI study</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>