Michels, Birgit Saumweber, Timo Biernacki, Roland Thum, Jeanette Glasgow, Rupert D. V. Schleyer, Michael Chen, Yi-chun Eschbach, Claire Stocker, Reinhard F. Toshima, Naoko Tanimura, Teiichi Louis, Matthieu Arias-Gil, Gonzalo Marescotti, Manuela Benfenati, Fabio Gerber, Bertram 2017 Larval Drosophila offer a study case for behavioral neurogenetics that is simple enough to be experimentally tractable, yet complex enough to be worth the effort. We provide a detailed, hands-on manual for Pavlovian odor-reward learning in these animals. Given the versatility of Drosophila for genetic analyses, combined with the evolutionarily shared genetic heritage with humans, the paradigm has utility not only in behavioral neurogenetics and experimental psychology, but for translational biomedicine as well. Together with the upcoming total synaptic connectome of the Drosophila nervous system and the possibilities of single-cell-specific transgene expression, it offers enticing opportunities for research. Indeed, the paradigm has already been adopted by a number of labs and is robust enough to be used for teaching in classroom settings. This has given rise to a demand for a detailed, hands- on manual directed at newcomers and/or at laboratory novices, and this is what we here provide. application/pdf https://folia.unifr.ch/global/documents/305384 https://folia.unifr.ch/documents/305384/files/sto_pcl.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.3389/fnbeh.2017.00045 info:eu-repo/semantics/openAccess License undefined Frontiers in Behavioral Neuroscience / Published version ; http://dx.doi.org/10.3389/fnbeh.2017.00045. - 2017, vol. 11, p. 45 info:eu-repo/classification/udc/57 Pavlovian conditioning of larval drosophila: an illustrated, multilingual, hands-on manual for odor-taste associative learning in maggots http://purl.org/coar/resource_type/c_6501