<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Shubchynskyy, Volodymyr</dc:creator>
  <dc:creator>Boniecka, Justyna</dc:creator>
  <dc:creator>Schweighofer, Alois</dc:creator>
  <dc:creator>Simulis, Justinas</dc:creator>
  <dc:creator>Kvederaviciute, Kotryna</dc:creator>
  <dc:creator>Stumpe, Michael</dc:creator>
  <dc:creator>Mauch, Felix</dc:creator>
  <dc:creator>Balazadeh, Salma</dc:creator>
  <dc:creator>Mueller-Roeber, Bernd</dc:creator>
  <dc:creator>Boutrot, Freddy</dc:creator>
  <dc:creator>Zipfel, Cyril</dc:creator>
  <dc:creator>Meskiene, Irute</dc:creator>
  <dc:date>2017</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Mitogen-activated protein kinases (MAPKs) mediate plant immune responses to  pathogenic bacteria. However, less is known about the cell autonomous negative  regulatory mechanism controlling basal plant immunity. We report the biological role of  Arabidopsis thaliana MAPK phosphatase AP2C1 as a negative regulator of plant basal  resistance and defense responses to Pseudomonas syringae. AP2C2, a closely  related MAPK phosphatase, also negatively controls plant resistance. Loss of AP2C1  leads to enhanced pathogen-induced MAPK activities, increased callose deposition in  response to pathogen-associated molecular patterns or to P. syringae pv. tomato (Pto)  DC3000, and enhanced resistance to bacterial infection with Pto. We also reveal the  impact of AP2C1 on the global transcriptional reprogramming of transcription factors  during Pto infection. Importantly, ap2c1 plants show salicylic acid-independent  transcriptional reprogramming of several defense genes and enhanced ethylene  production in response to Pto. This study pinpoints the specificity of MAPK regulation  by the different MAPK phosphatases AP2C1 and MKP1, which control the same MAPK  substrates, nevertheless leading to different downstream events. We suggest that  precise and specific control of defined MAPKs by MAPK phosphatases during plant  challenge with pathogenic bacteria can strongly influence plant resistance.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/305283</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/305283/files/mau_ppa.pdf</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/305283/files/mau_ppa_sm.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1093/jxb/erw485</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Journal of Experimental Botany. - 2017, vol. 68, no. 5, p. 1169-1183</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Callose</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Defense genes</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">MAPK</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">MAPK phosphatase</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">PAMP</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">PP2C phosphatase</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Pseudomonas syringae</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Salicylic acid</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Transcription factors</dc:subject>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns10="xml" ns10:lang="en">Protein phosphatase AP2C1 negatively regulates basal resistance and defense responses to Pseudomonas syringae</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>