<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Potron, Anaïs</dc:creator>
  <dc:creator>Poirel, Laurent</dc:creator>
  <dc:creator>Nordmann, Patrice</dc:creator>
  <dc:date>2014-01-01</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The current emergence of the carbapenemase OXA-48 among Enterobacteriaceae is related to the spread of a single IncL/M-type plasmid, pOXA-48a. This plasmid harbors the &lt;em&gt;bla&lt;/em&gt;&lt;sub&gt;OXA-48&lt;/sub&gt; gene within a composite transposon, Tn&lt;em&gt;1999&lt;/em&gt;, which is inserted into the &lt;em&gt;tir&lt;/em&gt; gene, encoding a transfer inhibition protein. We showed that the insertion of Tn&lt;em&gt;1999&lt;/em&gt; into the &lt;em&gt;tir&lt;/em&gt; gene was involved in a higher transfer frequency of plasmid pOXA-48a. This may likely be the key factor for the successful dissemination of this plasmid.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/303473</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/303473/files/nor_dtp.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1128/AAC.01344-13</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Antimicrobial Agents and Chemotherapy. - 2013, vol. 58, no. 1, p. 467–471</dc:source>
  <dc:subject>info:eu-repo/classification/udc/61</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">Derepressed transfer properties leading to the efficient spread of the plasmid encoding carbapenemase OXA-48</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>