Débieux, Jean-Luc Bochet, Christian G. 2011-10-06 An all-photochemical synthesis of OGP(10–14){,} the biologically active part of an osteogenic growth peptide{,} was performed. This required the preparation of photochemically activable amino acids containing a 5{,}7-dinitroindoline derivative on the C-terminus and a photolabile Ddz protecting group on the N-terminus. The photochemical acyl transfer from the dinitroindoline to an incoming nucleophilic amino group{,} which creates the amide bond{,} requires an irradiation wavelength of 385 nm. The deprotection of the Ddz group requires a shorter wavelength (300 nm){,} thus making both successive processes compatible. application/pdf https://folia.unifr.ch/global/documents/302330 https://folia.unifr.ch/documents/302330/files/boc_aps.pdf https://folia.unifr.ch/documents/302330/files/boc_aps_sm.pdf eng info:eu-repo/semantics/altIdentifier/doi/10.1039/c1sc00700a info:eu-repo/semantics/openAccess License undefined Chemical Science. - 2012, vol. 3, no. 2, p. 405-406 info:eu-repo/classification/udc/54 The all-photochemical synthesis of an OGP(10–14) precursor http://purl.org/coar/resource_type/c_6501