<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Kuhn, Benjamin M.</dc:creator>
  <dc:creator>Geisler, Markus</dc:creator>
  <dc:creator>Bigler, Laurent</dc:creator>
  <dc:creator>Ringli, Christoph</dc:creator>
  <dc:date>2011-01-01</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Flavonoids represent a class of secondary metabolites with diverse functions in plants including UV protection, pathogen defence, and interspecies communication. They are also known as modulators of signalling processes in plant and animal systems and therefore are considered to have beneficial effects as nutraceuticals. The &lt;em&gt;rol1-2&lt;/em&gt; (&lt;em&gt;repressor of lrx1&lt;/em&gt;) mutation of &lt;em&gt;Arabidopsis thaliana &lt;/em&gt;induces aberrant accumulation of flavonols and a cell-growth phenotype in the shoot. The hyponastic cotyledons, aberrant shape of pavement cells, and deformed trichomes in &lt;em&gt;rol1-2&lt;/em&gt; mutants are suppressed by blocking flavonoid biosynthesis, suggesting that the altered flavonol accumulation in these plants induces the shoot phenotype. Indeed, the identification of several &lt;em&gt;tt&lt;/em&gt; (&lt;em&gt;transparent testa &lt;/em&gt;), &lt;em&gt;myb&lt;/em&gt;, and &lt;em&gt;fls1&lt;/em&gt; (&lt;em&gt;flavonol synthase1&lt;/em&gt;) alleles in a &lt;em&gt;rol1-2&lt;/em&gt; suppressor screen provides genetic evidence that flavonols interfere with shoot development in &lt;em&gt;rol1-2&lt;/em&gt; seedlings. The increased accumulation of auxin in &lt;em&gt;rol1-2&lt;/em&gt; seedlings appears to be induced by a flavonol-induced modification of auxin transport. Quantification of auxin export from mesophyll protoplasts revealed that NAA but not IAA transport is affected by the &lt;em&gt;rol1-2&lt;/em&gt; mutation. Inhibition of flavonol biosynthesis in &lt;em&gt;rol1-2 fls1-3&lt;/em&gt; restores NAA transport to wild-type levels, indicating a very specific mode of action of flavonols on the auxin transport machinery.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/301859</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/301859/files/gei_faa.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1104/pp.111.175976</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Plant Physiology. - 2011, vol. 156, no. 2, p. 585-595</dc:source>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">Flavonols accumulate asymmetrically and affect auxin transport in Arabidopsis thaliana</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>