<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Vellai, Tibor</dc:creator>
  <dc:creator>Takacs-Vellai, Krisztina</dc:creator>
  <dc:creator>Zhang, Yue</dc:creator>
  <dc:creator>Kovacs, Attila L.</dc:creator>
  <dc:creator>Orosz, László</dc:creator>
  <dc:creator>Müller, Fritz</dc:creator>
  <dc:date>2003-12-11</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The group of enzymes known as TOR (for 'target of rapamycin') kinases regulates cell growth and proliferation in response to nutrients and hormone-dependent mitogenic signals&lt;sup&gt;1, 2&lt;/sup&gt;. Here we show that TOR deficiency in the nematode &lt;i&gt;Caenorhabditis elegans&lt;/i&gt; more than doubles its natural lifespan. This new function for TOR signalling in ageing control may represent a link between nutrition, metabolism and longevity.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://folia.unifr.ch/global/documents/300051</dc:identifier>
  <dc:identifier>https://folia.unifr.ch/documents/300051/files/muller_itk.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1038/426620a</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Nature. - 2003, vol. 426, p. 620</dc:source>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">Influence of TOR kinase on lifespan in C. elegans</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>